NDC codes

FDA NDC Directory
Product NDC (as listed)0088-2161Labeler and product segments. Claims need a package NDC.
Product NDC at billing width00088-2161Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
0088-2161-30000882161301 BOTTLE in 1 CARTON (0088-2161-30) / 30 TABLET, FILM COATED in 1 BOTTLEMarketed from Sep 19, 1998

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Arava
Generic name (nonproprietary)
leflunomide
Active ingredients
Leflunomide — 20 mg/1
Dosage form
Tablet, Film coated
Route
Oral
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 020905
Marketing start
Listing expires
Identifiers
Product ID 0088-2161_765327c7-cb5b-4637-84da-4fd9a024ad96SPL ID 765327c7-cb5b-4637-84da-4fd9a024ad96SPL set ID 320f63f2-fac3-4aee-aff8-85724e00ef52RxCUI 205284, 205285, 205286, 213377, 213379, 213380UNII G162GK9U4W
Pharmacologic class
Antirheumatic Agent

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400088216130 followed by a unit qualifier and the quantity

Package 00088-2161-30. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

ARAVA is indicated for the treatment of adults with active rheumatoid arthritis (RA). ARAVA is a pyrimidine synthesis inhibitor indicated for the treatment of adults with active rheumatoid arthritis. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 020905

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 020905
ProductStrengthForm · routeLabelerProduct NDC
AravaleflunomideLeflunomide 10 mg/1Tablet, Film coatedOralsanofi-aventis U.S. LLC0088-2160
AravaleflunomideLeflunomide 100 mg/1Tablet, Film coatedOralsanofi-aventis U.S. LLC0088-2162

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