Bupropion Hydrochloride NDC 31722-487

NDC codes

FDA NDC Directory

Product NDC (as listed)31722-487Labeler and product segments. Claims need a package NDC.

Product NDC at billing width31722-0487Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
31722-487-05	31722048705	500 TABLET, EXTENDED RELEASE in 1 BOTTLE (31722-487-05)Marketed from Oct 1, 2025
31722-487-30	31722048730	30 TABLET, EXTENDED RELEASE in 1 BOTTLE (31722-487-30)Marketed from Oct 1, 2025
31722-487-90	31722048790	90 TABLET, EXTENDED RELEASE in 1 BOTTLE (31722-487-90)Marketed from Oct 1, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Bupropion Hydrochloride
Generic name (nonproprietary): bupropion hydrochloride
Active ingredients: Bupropion hydrochloride — 150 mg/1
Dosage form: Tablet, Extended release
Route: Oral
Labeler: Camber Pharmaceuticals, Inc.
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 217898
Marketing start: Oct 1, 2025
Listing expires: Dec 31, 2027
Other FDA classes: Dopamine Uptake Inhibitors (Mechanism)Increased Dopamine Activity (Physiologic effect)Increased Norepinephrine Activity (Physiologic effect)Norepinephrine Uptake Inhibitors (Mechanism)
Identifiers: Product ID 31722-487_500b524c-53eb-26fe-e063-6394a90a8da7SPL ID 500b524c-53eb-26fe-e063-6394a90a8da7SPL set ID c71f18b7-36a3-4489-96b4-e8fbec4f73a1RxCUI 993541, 993557UNII ZG7E5POY8OUPC 0331722488303
Pharmacologic class: Aminoketone

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N431722048705 followed by a unit qualifier and the quantity

Package 31722-0487-05. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Apr 22, 2026. This label includes a boxed warning.

Indications (excerpt from the label)

Bupropion hydrochloride extended-release tablets (XL) are an aminoketone antidepressant, indicated for: • treatment of major depressive disorder (MDD) ( 1.1 ) • prevention of seasonal affective disorder (SAD) ( 1.2 ) 1.1 Major Depressive Disorder (MDD) Bupropion hydrochloride extended-release tablets (XL) are indicated for the treatment of major depressive disorder (MDD), as defined by the Diagnostic and Statistical Manual (DSM). The efficacy of the immediate-release formulation of bupropion was established in two 4-week controlled inpatient trials and one 6-week controlled outpatient trial of adult patients with MDD. The efficacy of the sustained-release formulation of bupropion in the main…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 217898

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 217898
Product	Strength	Form · route	Labeler	Product NDC
Bupropion Hydrochloride	Bupropion hydrochloride 300 mg/1	Tablet, Extended releaseOral	Camber Pharmaceuticals, Inc.	31722-488