NDC codes

FDA NDC Directory
Product NDC (as listed)71335-1772Labeler and product segments. Claims need a package NDC.
Product NDC at billing width71335-1772Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
71335-1772-17133517720130 TABLET in 1 BOTTLE (71335-1772-1)Marketed from Dec 29, 2021
71335-1772-27133517720212 TABLET in 1 BOTTLE (71335-1772-2)Marketed from Dec 29, 2021
71335-1772-37133517720320 TABLET in 1 BOTTLE (71335-1772-3)Marketed from Dec 29, 2021
71335-1772-471335177204100 TABLET in 1 BOTTLE (71335-1772-4)Marketed from Dec 29, 2021
71335-1772-57133517720536 TABLET in 1 BOTTLE (71335-1772-5)Marketed from Dec 29, 2021
71335-1772-67133517720624 TABLET in 1 BOTTLE (71335-1772-6)Marketed from Jan 21, 2021
71335-1772-77133517720790 TABLET in 1 BOTTLE (71335-1772-7)Marketed from Dec 29, 2021
71335-1772-8713351772084 TABLET in 1 BOTTLE (71335-1772-8)Marketed from Dec 29, 2021

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Methotrexate
Generic name (nonproprietary)
methotrexate
Active ingredients
Methotrexate sodium — 2.5 mg/1
Dosage form
Tablet
Route
Oral
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 213343
Marketing start
Listing expires
Other FDA classes
Folic Acid Metabolism Inhibitors (Mechanism)
Identifiers
Product ID 71335-1772_17125571-6b01-40cb-ab78-7b9f4f8cc16cSPL ID 17125571-6b01-40cb-ab78-7b9f4f8cc16cSPL set ID 4741a44f-0d0b-4380-84f6-231a8d1560fbRxCUI 105585UNII 3IG1E710ZN
Pharmacologic class
Folate Analog Metabolic Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N471335177201 followed by a unit qualifier and the quantity

Package 71335-1772-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

Methotrexate tablets is a dihydrofolate reductase inhibitor indicated for the: Treatment of adults and pediatric patients with acute lymphoblastic leukemia (ALL) as part of a combination chemotherapy maintenance regimen ( 1.1 ) Treatment of adults with mycosis fungoides ( 1.1 ) Treatment of adults with relapsed or refractory non-Hodgkin lymphoma as part of a metronomic combination regimen ( 1.1 ) Treatment of adults with rheumatoid arthritis ( 1.2 ) Treatment of pediatric patients with polyarticular juvenile idiopathic arthritis (pJIA) ( 1.3 ) Treatment of adults with severe psoriasis ( 1.4 ) 1.1 Neoplastic Diseases is indicated for the: Methotrexate Tablets is indicated for the: treatment o…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 213343

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 213343
ProductStrengthForm · routeLabelerProduct NDC
MethotrexateMethotrexate sodium 2.5 mg/1TabletOralProficient Rx LP82804-136
MethotrexateMethotrexate sodium 2.5 mg/1TabletOralCoupler LLC67046-1524
MethotrexateMethotrexate sodium 2.5 mg/1TabletOralAccord Healthcare Inc.16729-486
MethotrexateMethotrexate sodium 2.5 mg/1TabletOralNuCare Pharmaceuticals, Inc.68071-3991

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