Prometrium (progesterone) NDC 72989-373

NDC codes

FDA NDC Directory

Product NDC (as listed)72989-373Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72989-0373Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72989-373-30	72989037330	30 CAPSULE in 1 BOTTLE (72989-373-30)Marketed from Nov 1, 2022

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Prometrium
Generic name (nonproprietary): progesterone
Active ingredients: Progesterone — 200 mg/1
Dosage form: Capsule
Route: Oral
Labeler: Acertis Pharmaceuticals, LLC
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 019781
Marketing start: Nov 1, 2022
Listing expires: Dec 31, 2027
Other FDA classes: Progesterone (Chemical structure)
Identifiers: Product ID 72989-373_4ff93bfe-305d-4956-bec9-5ac1d469b34fSPL ID 4ff93bfe-305d-4956-bec9-5ac1d469b34fSPL set ID 1cf237ff-c4f8-4faa-a7aa-77599c856889RxCUI 260243, 261319, 262080, 312641UNII 4G7DS2Q64YUPC 0372989372301, 0372989373308
Pharmacologic class: Progesterone

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472989037330 followed by a unit qualifier and the quantity

Package 72989-0373-30. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jul 23, 2026.

Indications (excerpt from the label)

INDICATIONS AND USAGE PROMETRIUM ® (progesterone, USP) Capsules are indicated for use in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving conjugated estrogens tablets. They are also indicated for use in secondary amenorrhea.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 019781

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 019781
Product	Strength	Form · route	Labeler	Product NDC
Prometriumprogesterone	Progesterone 100 mg/1	CapsuleOral	Acertis Pharmaceuticals, LLC	72989-372