OpenGeneral StudyTreatment Study

ADOLESCENTS IMAGING USING fMRI: Feasibility Study

For Condition: Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD GroupFor Condition: Diagnosis of ADHD Using the KSADS-PL for the ADHD GroupFor Condition: Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control GroupFor Condition: All Participants Were Euthymic at the Time of Task Administration

ID: NCT07540429

Horizon Patient Guidance Summary

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How it’s taken

Diet & Lifestyle / Therapy Care

Expected Availability Horizon

General Study

StageGeneral evaluation study exploring treatment methods.

EligibleHealthy volunteers welcome — you do not need to be diagnosed with the condition to participate.

About This Clinical Trial

Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents with BPD. This study aims to increase knowledgements related to neural correlates of BPD and clinical disorders.

Study Timeline & Quick Facts

Trial Status

Open — Looking for Participants

Total Target Enrollment

21 patients (Estimated)

Study Start Date

2024-06-08

Est. Primary Completion

2027-06-08

Tested Drugs & Treatment Groups

DIAGNOSTIC_TESTfunctional magnetic resonance imaging (fMRI)

Investigators used fMRI to compare patterns of regional brain activation between three groups of adolescents girls: Six female adolescents meeting criteria for BPD, 6 female adolescents meeting criteria of ADHD and 6 female adolescents without psychiatric disorder were recruited.

Treatment Arms Description

OTHERHealthy adolescent girl volunteers

The participants will follow the same study plan

OTHERAdolescent girls with borderline personality disorder

The participants will follow the same study plan

OTHERAdolescent girls with Attention Deficit Hyperactivity Disorder

The participants will follow the same study plan

Can I Join This Study?

Suitable For

Women only

Ages Welcome

Between 12 Years and 17 Years

Full Criteria Checklist

Who Can Join

Female adolescents meeting DIB-R criteria for BPD group
Female adolescents meeting kSADS-PL for ADHD group
Female adolescents without any psychologic disorders

Who Cannot Join

Any medical history with head trauma, chronic neurologic disease, any contraindications for fRMI, claustrophobia or pregnancy.

What is this Study Measuring?

Primary Outcome Measures

MRI-Acquired Activation Mapping — Time Frame: 2 years
Establishment of activation maps by statistical analysis of local signal variations to locate functional regions essential to motor skills and language.

View Secondary Outcome Measures (1)

Feasibility of this study — Time Frame: 2 years
Pilot feasibility study with a small sample size

Where to Participate

This trial is recruiting at 1 study facilities worldwide. Click below to see if there is a clinic or hospital in your area:

Show All 1 Facilities & Contact Sites

EPSM de la Somme

Dury, France

Status: Open

Trial Design & Scientific Setup

Allocation

non_randomized

Intervention Model

parallel

Primary Purpose

diagnostic

Masking

single (participant)

Sponsoring Teams & Contacts

Lead Sponsoring Institution

Etablissement Public de la Sante Mentale de la Somme

Collaborators: Centre Hospitalier Universitaire, Amiens

Primary Research Contact

MICHAEL MONET, PhD

Tel: 0322534612

Email: unite.2.recherche@epsm-somme.fr

Clinical Trial Application Copilot

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Subject: Inquiry about clinical trial enrollment: NCT07540429 - ADOLESCENTS IMAGING USING fMRI: Feasibility Study

Dear Study Coordinator / Research Team, I hope this message finds you well. My name is [Your Name], and I am writing to express my strong interest in participating in the clinical trial titled "ADOLESCENTS IMAGING USING fMRI: Feasibility Study" (NCT ID: NCT07540429). I am [Age] years old and have been diagnosed with Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group. I have reviewed the eligibility criteria for this study on Med Code Info and believe I may be a suitable candidate. Could you please let me know if this study is actively enrolling patients at any site near my location, and what the next steps are to undergo screening? Thank you for your time and research efforts. Warm regards, [Your Name]

Scientific Literature & Publications

Guile JM, Boissel L, Alaux-Cantin S, de La Riviere SG. Borderline personality disorder in adolescents: prevalence, diagnosis, and treatment strategies. Adolesc Health Med Ther. 2018 Nov 23;9:199-210. doi: 10.2147/AHMT.S156565. eCollection 2018.PubMed ↗

View Official Medical/Scientific Title

Feasibility Study Using Functional Magnetic Resonance Imaging (fMRI) on Bordeline Personality Disorders in Adolescents