How many J7186 billing units are in a package of Alphanate?

CMS lists 1 billing units per package, depending on the NDC, where one unit is per factor viii IU. Units to report are based on the dose given, not the package.

No. J7186 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Alphanate J-Code J7186 — Billing Units & NDCs

In short

Alphanate is billed under HCPCS J7186 — Injection, antihemophilic factor viii/von willebrand factor complex (human), per factor viii i.u.. One billing unit is per factor viii IU. CMS's crosswalk lists 5 Alphanate NDCs under this code.

J7186 code details

Reference

J7186: Injection, antihemophilic factor viii/von willebrand factor complex (human), per factor viii i.u.Billing unit: per factor viii IU
Labelers: Grifols USA, LLC

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$1.267

Perper factor viii iu

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Alphanate units and claim line

Enter the dose given to get the J7186 units and the NDC line for the CMS-1500 and the 837P.

HCPCS units

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the units to build the claim line.

Alphanate NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Alphanate NDCs in the CMS ASP crosswalk
NDC (11-digit)	HCPCS	Labeler	Package	Billing units per package
68516-4616-01	J7186	Grifols USA, LLC	1	1
68516-4617-01	J7186	Grifols USA, LLC	1	1
68516-4618-02	J7186	Grifols USA, LLC	1	1
68516-4619-02	J7186	Grifols USA, LLC	1	1
68516-4620-02	J7186	Grifols USA, LLC	1	1

Alphanate: common questions

What is the J-code for Alphanate?: Alphanate is billed under HCPCS J7186 — Injection, antihemophilic factor viii/von willebrand factor complex (human), per factor viii i.u.. One billing unit is per factor viii IU. CMS's crosswalk lists 5 Alphanate NDCs under this code.
How many J7186 billing units are in a package of Alphanate?: CMS lists 1 billing units per package, depending on the NDC, where one unit is per factor viii IU. Units to report are based on the dose given, not the package.
Is J7186 a CPT code?: No. J7186 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Alphanate J-Code / HCPCS Code