How many J0278 billing units are in a package of Amikacin Sulfate?

CMS lists 50 to 100 billing units per package, depending on the NDC, where one unit is 100 mg. Units to report are based on the dose given, not the package.

No. J0278 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Amikacin Sulfate J-Code J0278 — Billing Units & NDCs

In short

Amikacin Sulfate is billed under HCPCS J0278 — Injection, amikacin sulfate, 100 mg. One billing unit is 100 mg. CMS's crosswalk lists 12 Amikacin Sulfate NDCs under this code.

J0278 code details

Reference

J0278: Injection, amikacin sulfate, 100 mgBilling unit: 100 mg
Labelers: FreseniUS Kabi USA, LLC; Heritage Pharmaceuticals Inc.; Hikma Pharmaceuticals USA Inc.; Mullan Pharmaceutical Inc.; Sagent Pharmaceuticals

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$0.612

Per100 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Amikacin Sulfate units and claim line

Enter the dose given to get the J0278 units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 100 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Amikacin Sulfate NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Amikacin Sulfate NDCs in the CMS ASP crosswalk
NDC (11-digit)	HCPCS	Labeler	Package	Billing units per package
00641-6166-10	J0278	Hikma Pharmaceuticals USA Inc.	10 × 4	100
00641-6167-10	J0278	Hikma Pharmaceuticals USA Inc.	10 × 2	50
23155-0290-41	J0278	Heritage Pharmaceuticals Inc.	10 × 2	50
23155-0290-42	J0278	Heritage Pharmaceuticals Inc.	10 × 4	100
23155-0785-41	J0278	Heritage Pharmaceuticals Inc.	10 × 2	50
23155-0786-41	J0278	Heritage Pharmaceuticals Inc.	10 × 4	100
25021-0173-02	J0278	Sagent Pharmaceuticals	10 × 2	50
25021-0173-04	J0278	Sagent Pharmaceuticals	10 × 4	100
63323-0815-02	J0278	FreseniUS Kabi USA, LLC	10 × 2	50
63323-0815-04	J0278	FreseniUS Kabi USA, LLC	10 × 4	100
83301-0022-02	J0278	Mullan Pharmaceutical Inc.	10 × 2	50
83301-0023-02	J0278	Mullan Pharmaceutical Inc.	10 × 4	100

Amikacin Sulfate: common questions

What is the J-code for Amikacin Sulfate?: Amikacin Sulfate is billed under HCPCS J0278 — Injection, amikacin sulfate, 100 mg. One billing unit is 100 mg. CMS's crosswalk lists 12 Amikacin Sulfate NDCs under this code.
How many J0278 billing units are in a package of Amikacin Sulfate?: CMS lists 50 to 100 billing units per package, depending on the NDC, where one unit is 100 mg. Units to report are based on the dose given, not the package.
Is J0278 a CPT code?: No. J0278 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Amikacin Sulfate J-Code / HCPCS Code