In short

Amphotericin B is billed under HCPCS J0285 — Injection, amphotericin b, 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 1 Amphotericin B NDC under this code.

J0285 code details

Reference

J0285
Injection, amphotericin b, 50 mgBilling unit: 50 mg
Labelers
XGen Pharmaceuticals DJB, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$42.474
Per50 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Amphotericin B units and claim line

Enter the dose given to get the J0285 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Amphotericin B NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Amphotericin B NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
39822-1055-05J0285XGen Pharmaceuticals DJB, Inc.11

Amphotericin B: common questions

What is the J-code for Amphotericin B?
Amphotericin B is billed under HCPCS J0285 — Injection, amphotericin b, 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 1 Amphotericin B NDC under this code.
How many J0285 billing units are in a package of Amphotericin B?
CMS lists 1 billing units per package, depending on the NDC, where one unit is 50 mg. Units to report are based on the dose given, not the package.
Is J0285 a CPT code?
No. J0285 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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