In short

Amphotericin B Liposome is billed under HCPCS J0289 — Injection, amphotericin b liposome, 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 4 Amphotericin B Liposome NDCs under this code.

J0289 code details

Reference

J0289
Injection, amphotericin b liposome, 10 mgBilling unit: 10 mg
Labelers
Eugia US LLC; Heritage Pharmaceuticals Inc.; Mylan Institutional LLC; Sun Pharmaceutical Industries, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$17.851
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Amphotericin B Liposome units and claim line

Enter the dose given to get the J0289 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Amphotericin B Liposome NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Amphotericin B Liposome NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
23155-0594-31J0289Heritage Pharmaceuticals Inc.15
55150-0365-01J0289Eugia US LLC15
62756-0233-01J0289Sun Pharmaceutical Industries, Inc.15
67457-0926-50J0289Mylan Institutional LLC15

Amphotericin B Liposome: common questions

What is the J-code for Amphotericin B Liposome?
Amphotericin B Liposome is billed under HCPCS J0289 — Injection, amphotericin b liposome, 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 4 Amphotericin B Liposome NDCs under this code.
How many J0289 billing units are in a package of Amphotericin B Liposome?
CMS lists 5 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
Is J0289 a CPT code?
No. J0289 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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