In short

Astagraf XL is billed under HCPCS J7508 — Tacrolimus, extended release, (astagraf xl), oral, 0.1 mg. One billing unit is 0.1 mg. CMS's crosswalk lists 3 Astagraf XL NDCs under this code.

J7508 code details

Reference

J7508
Tacrolimus, extended release, (astagraf xl), oral, 0.1 mgBilling unit: 0.1 mg
Labelers
Astellas Pharma US, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.604
Per0.1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Astagraf XL units and claim line

Enter the dose given to get the J7508 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Astagraf XL NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Astagraf XL NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00469-0647-73J7508Astellas Pharma US, Inc.30150
00469-0677-73J7508Astellas Pharma US, Inc.30300
00469-0687-73J7508Astellas Pharma US, Inc.301500

Astagraf XL: common questions

What is the J-code for Astagraf XL?
Astagraf XL is billed under HCPCS J7508 — Tacrolimus, extended release, (astagraf xl), oral, 0.1 mg. One billing unit is 0.1 mg. CMS's crosswalk lists 3 Astagraf XL NDCs under this code.
How many J7508 billing units are in a package of Astagraf XL?
CMS lists 150 to 1,500 billing units per package, depending on the NDC, where one unit is 0.1 mg. Units to report are based on the dose given, not the package.
Is J7508 a CPT code?
No. J7508 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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