In short

Benlysta is billed under HCPCS J0490 — Injection, belimumab, 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 2 Benlysta NDCs under this code.

J0490 code details

Reference

J0490
Injection, belimumab, 10 mgBilling unit: 10 mg
Labelers
GlaxoSmithKline LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$58.333
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Benlysta units and claim line

Enter the dose given to get the J0490 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Benlysta NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Benlysta NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
49401-0101-01J0490GlaxoSmithKline LLC512
49401-0102-01J0490GlaxoSmithKline LLC2040

Benlysta: common questions

What is the J-code for Benlysta?
Benlysta is billed under HCPCS J0490 — Injection, belimumab, 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 2 Benlysta NDCs under this code.
How many J0490 billing units are in a package of Benlysta?
CMS lists 12 to 40 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
Is J0490 a CPT code?
No. J0490 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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