In short

CMS assigns Bortezomib NDCs to 2 HCPCS codes: J9041 (per 0.1 mg), J9049 (per 0.1 mg). Which one applies depends on the product; the table lists each NDC with its code.

J9041 code detailsJ9049 code details

Reference

J9041
Injection, bortezomib, 0.1 mgBilling unit: 0.1 mg
J9049
Injection, bortezomib (hospira), not therapeutically equivalent to j9041, 0.1 mgBilling unit: 0.1 mg
Labelers
Apotex Corp; Athenex Pharmaceutical Division, LLC; Baxter Healthcare Corporation; BluePoint Laboratories; Dr. Reddy's Laboratories Inc.; Eugia US LLC; FreseniUS Kabi USA, LLC; Hikma Pharmaceuticals USA Inc.and 8 more

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$2.628
Per0.1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$1.531
Per0.1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Bortezomib units and claim line

Enter the dose given to get the J9041 units and the NDC line for the CMS-1500 and the 837P. This builds the J9041 line; use the code page for J9049.

Enter the dose given to build the claim line.

Bortezomib NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Bortezomib NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00143-9098-01J9041Hikma Pharmaceuticals USA Inc.135
00409-1700-01J9041Pfizer Inc135
10019-0991-01J9041Baxter Healthcare Corporation135
25021-0244-10J9041Sagent Pharmaceuticals135
25021-0262-10J9041Sagent Pharmaceuticals135
43598-0426-60J9041Dr. Reddy's Laboratories Inc.135
50742-0484-01J9041Ingenus Pharmaceuticals LLC135
55150-0337-01J9041Eugia US LLC135
60505-6050-04J9041Apotex Corp135
63323-0821-10J9041FreseniUS Kabi USA, LLC135
68001-0534-36J9041BluePoint Laboratories135
68001-0540-36J9041BluePoint Laboratories135
68001-0541-36J9041BluePoint Laboratories135
70069-0836-01J9041Somerset Pharma, LLC135
70710-1411-01J9041Zydus Pharmaceuticals (USA) Inc.135
70860-0225-10J9041Athenex Pharmaceutical Division, LLC135
71288-0118-10J9041Meitheal Pharmaceuticals Inc.135
72205-0183-01J9041Novadoz Pharmaceuticals LLC135
72603-0270-01J9041Northstar RxLLC135
00409-1703-01J9049Pfizer Inc125
00409-1704-01J9049Pfizer Inc110

Bortezomib: common questions

What is the J-code for Bortezomib?
CMS assigns Bortezomib NDCs to 2 HCPCS codes: J9041 (per 0.1 mg), J9049 (per 0.1 mg). Which one applies depends on the product; the table lists each NDC with its code.
How many J9041 billing units are in a package of Bortezomib?
CMS lists 35 billing units per package, depending on the NDC, where one unit is 0.1 mg. Units to report are based on the dose given, not the package.
How many J9049 billing units are in a package of Bortezomib?
CMS lists 10 to 25 billing units per package, depending on the NDC, where one unit is 0.1 mg. Units to report are based on the dose given, not the package.
Is J9041 a CPT code?
No. J9041 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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