In short

Breyanzi is billed under HCPCS Q2054. One billing unit is up to 110 million car-positive viable t cells, per therapeutic dose. CMS's crosswalk lists 1 Breyanzi NDC under this code.

Q2054 code details

Reference

Q2054
HCPCS Level II drug codeBilling unit: up to 110 million car-positive viable t cells, per therapeutic dose
Labelers
Juno Therapeutics, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$589,846.771
Perup to 110 million car-positive viable t cells, per therapeutic dose
Coinsurance17.989%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Inflation-adjusted coinsurance. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Breyanzi units and claim line

Enter the dose given to get the Q2054 units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

Breyanzi NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Breyanzi NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
73153-0900-01Q2054Juno Therapeutics, Inc.11

Breyanzi: common questions

What is the HCPCS code for Breyanzi?
Breyanzi is billed under HCPCS Q2054. One billing unit is up to 110 million car-positive viable t cells, per therapeutic dose. CMS's crosswalk lists 1 Breyanzi NDC under this code.
How many Q2054 billing units are in a package of Breyanzi?
CMS lists 1 billing units per package, depending on the NDC, where one unit is up to 110 million car-positive viable t cells, per therapeutic dose. Units to report are based on the dose given, not the package.
Is Q2054 a CPT code?
No. Q2054 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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