HCPCS drug code · CMS crosswalk
Busulfan J-Code / HCPCS Code
In short
Busulfan is billed under HCPCS J0594 — injection, busulfan, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 7 Busulfan NDCs under this code.
Reference
- J0594
- injection, busulfan, 1 mgBilling unit: 1 mg
- Labelers
- Accord Healthcare Inc; Athenex Pharmaceutical Division, LLC; Meitheal Pharmaceuticals Inc.; Mylan Institutional LLC; Otsuka America Pharmaceuticals Inc.; Pfizer Inc; Sagent Pharmaceuticals
Medicare Part B payment limit
CMS ASP filePayment limit per unit$0.839
Per1 mg
Coinsurance20%
Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Busulfan units and claim line
Enter the dose given to get the J0594 units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Busulfan NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 00409-1112-01 | J0594 | Pfizer Inc | 8 × 10 | 480 |
| 16729-0351-92 | J0594 | Accord Healthcare Inc | 8 × 10 | 480 |
| 25021-0241-10 | J0594 | Sagent Pharmaceuticals | 8 × 10 | 480 |
| 59148-0070-91 | J0594 | Otsuka America Pharmaceuticals Inc. | 8 × 10 | 480 |
| 67457-0893-08 | J0594 | Mylan Institutional LLC | 8 × 10 | 480 |
| 70860-0216-10 | J0594 | Athenex Pharmaceutical Division, LLC | 8 × 10 | 480 |
| 71288-0116-11 | J0594 | Meitheal Pharmaceuticals Inc. | 8 × 10 | 480 |
Busulfan: common questions
- What is the J-code for Busulfan?
- Busulfan is billed under HCPCS J0594 — injection, busulfan, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 7 Busulfan NDCs under this code.
- How many J0594 billing units are in a package of Busulfan?
- CMS lists 480 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
- Is J0594 a CPT code?
- No. J0594 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.