In short

Crysvita is billed under HCPCS J0584 — Injection, burosumab-twza 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 3 Crysvita NDCs under this code.

J0584 code details

Reference

J0584
Injection, burosumab-twza 1 mgBilling unit: 1 mg
Labelers
Kyowa Kirin, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$516.85
Per1 mg
Coinsurance18.18%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Inflation-adjusted coinsurance. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Crysvita units and claim line

Enter the dose given to get the J0584 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Crysvita NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Crysvita NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
42747-0102-01J0584Kyowa Kirin, Inc.110
42747-0203-01J0584Kyowa Kirin, Inc.120
42747-0304-01J0584Kyowa Kirin, Inc.130

Crysvita: common questions

What is the J-code for Crysvita?
Crysvita is billed under HCPCS J0584 — Injection, burosumab-twza 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 3 Crysvita NDCs under this code.
How many J0584 billing units are in a package of Crysvita?
CMS lists 10 to 30 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
Is J0584 a CPT code?
No. J0584 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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