In short

Cyclosporine Injection is billed under HCPCS J7516 — Injection, cyclosporine, 250 mg. One billing unit is 250 mg. CMS's crosswalk lists 1 Cyclosporine Injection NDC under this code.

J7516 code details

Reference

J7516
Injection, cyclosporine, 250 mgBilling unit: 250 mg
Labelers
Padagis US LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$75.649
Per250 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Cyclosporine Injection units and claim line

Enter the dose given to get the J7516 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Cyclosporine Injection NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Cyclosporine Injection NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00574-0866-10J7516Padagis US LLC10 × 510

Cyclosporine Injection: common questions

What is the J-code for Cyclosporine Injection?
Cyclosporine Injection is billed under HCPCS J7516 — Injection, cyclosporine, 250 mg. One billing unit is 250 mg. CMS's crosswalk lists 1 Cyclosporine Injection NDC under this code.
How many J7516 billing units are in a package of Cyclosporine Injection?
CMS lists 10 billing units per package, depending on the NDC, where one unit is 250 mg. Units to report are based on the dose given, not the package.
Is J7516 a CPT code?
No. J7516 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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