In short

Diphenhydramine HCl is billed under HCPCS J1200 — Injection, diphenhydramine hcl, up to 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 18 Diphenhydramine HCl NDCs under this code.

J1200 code details

Reference

J1200
Injection, diphenhydramine hcl, up to 50 mgBilling unit: 50 mg
Labelers
A-S Medication Solutions; Armas Pharmaceuticals Inc.; Avenacy Inc.; FreseniUS Kabi USA, LLC; HF Acquisition Co. LLC, DBA HealthFirst; Henry Schein Inc.; Heritage Pharmaceuticals Inc.; Hikma Pharmaceuticals USA Inc.and 2 more

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.855
Per50 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Diphenhydramine HCl units and claim line

Enter the dose given to get the J1200 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Diphenhydramine HCl NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Diphenhydramine HCl NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00641-0376-25J1200Hikma Pharmaceuticals USA Inc.25 × 125
63323-0664-01J1200FreseniUS Kabi USA, LLC25 × 125
63323-0664-16J1200FreseniUS Kabi USA, LLC25 × 125
72485-0101-25J1200Armas Pharmaceuticals Inc.25 × 125
76045-0102-10J1200FreseniUS Kabi USA, LLC24 × 124
00404-9851-01J1200Henry Schein Inc.11
00641-6282-25J1200Hikma Pharmaceuticals USA Inc.25 × 125
23155-0263-31J1200Heritage Pharmaceuticals Inc.1010
23155-0264-41J1200Heritage Pharmaceuticals Inc.25 × 125
25021-0481-01J1200Sagent Pharmaceuticals25 × 125
42571-0337-87J1200Micro Labs Limited25 × 125
42571-0511-56J1200Micro Labs Limited1010
50090-0878-00J1200A-S Medication Solutions11
50090-1841-00J1200A-S Medication Solutions25 × 125
51662-1219-01J1200HF Acquisition Co. LLC, DBA HealthFirst11
51662-1219-03J1200HF Acquisition Co. LLC, DBA HealthFirst25 × 125
72485-0101-05J1200Armas Pharmaceuticals Inc.5 × 15
83634-0781-01J1200Avenacy Inc.25 × 125

Diphenhydramine HCl: common questions

What is the J-code for Diphenhydramine HCl?
Diphenhydramine HCl is billed under HCPCS J1200 — Injection, diphenhydramine hcl, up to 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 18 Diphenhydramine HCl NDCs under this code.
How many J1200 billing units are in a package of Diphenhydramine HCl?
CMS lists 1 to 25 billing units per package, depending on the NDC, where one unit is 50 mg. Units to report are based on the dose given, not the package.
Is J1200 a CPT code?
No. J1200 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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