HCPCS drug code · CMS crosswalk
Enhertu J-Code / HCPCS Code
In short
Enhertu is billed under HCPCS J9358 — Injection, fam-trastuzumab deruxtecan-nxki, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 1 Enhertu NDC under this code.
Reference
- J9358
- Injection, fam-trastuzumab deruxtecan-nxki, 1 mgBilling unit: 1 mg
- Labelers
- Daiichi Sankyo Inc.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Inflation-adjusted coinsurance. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Enhertu units and claim line
Enter the dose given to get the J9358 units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Enhertu NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 65597-0406-01 | J9358 | Daiichi Sankyo Inc. | 1 | 100 |
Enhertu: common questions
- What is the J-code for Enhertu?
- Enhertu is billed under HCPCS J9358 — Injection, fam-trastuzumab deruxtecan-nxki, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 1 Enhertu NDC under this code.
- How many J9358 billing units are in a package of Enhertu?
- CMS lists 100 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
- Is J9358 a CPT code?
- No. J9358 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.