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Erythromycin Lactobionate is billed under HCPCS J1364 — Injection, erythromycin lactobionate, per 500 mg. One billing unit is 500 mg. CMS's crosswalk lists 3 Erythromycin Lactobionate NDCs under this code.

J1364 code details

Reference

J1364
Injection, erythromycin lactobionate, per 500 mgBilling unit: 500 mg
Labelers
Nexus Pharmaceuticals, LLC; Pfizer Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$160.427
Per500 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Erythromycin Lactobionate units and claim line

Enter the dose given to get the J1364 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Erythromycin Lactobionate NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Erythromycin Lactobionate NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00409-6476-44J1364Pfizer Inc10 × 110
00409-6482-01J1364Pfizer Inc10 × 1010
14789-0116-05J1364Nexus Pharmaceuticals, LLC5 × 15

Erythromycin Lactobionate: common questions

What is the J-code for Erythromycin Lactobionate?
Erythromycin Lactobionate is billed under HCPCS J1364 — Injection, erythromycin lactobionate, per 500 mg. One billing unit is 500 mg. CMS's crosswalk lists 3 Erythromycin Lactobionate NDCs under this code.
How many J1364 billing units are in a package of Erythromycin Lactobionate?
CMS lists 5 to 10 billing units per package, depending on the NDC, where one unit is 500 mg. Units to report are based on the dose given, not the package.
Is J1364 a CPT code?
No. J1364 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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