In short

Fabrazyme is billed under HCPCS J0180 — Injection, agalsidase beta, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 2 Fabrazyme NDCs under this code.

J0180 code details

Reference

J0180
Injection, agalsidase beta, 1 mgBilling unit: 1 mg
Labelers
Genzyme Corporation

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$230.54
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Fabrazyme units and claim line

Enter the dose given to get the J0180 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Fabrazyme NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Fabrazyme NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
58468-0040-01J0180Genzyme Corporation135
58468-0041-01J0180Genzyme Corporation15

Fabrazyme: common questions

What is the J-code for Fabrazyme?
Fabrazyme is billed under HCPCS J0180 — Injection, agalsidase beta, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 2 Fabrazyme NDCs under this code.
How many J0180 billing units are in a package of Fabrazyme?
CMS lists 5 to 35 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
Is J0180 a CPT code?
No. J0180 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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