In short

Gammagard S/D is billed under HCPCS J1566 — Injection, immune globulin, intravenous, lyophilized (e.g., powder), not otherwise specified, 500 mg. One billing unit is 500 mg. CMS's crosswalk lists 2 Gammagard S/D NDCs under this code.

J1566 code details

Reference

J1566
Injection, immune globulin, intravenous, lyophilized (e.g., powder), not otherwise specified, 500 mgBilling unit: 500 mg
Labelers
Takeda Pharmaceuticals America, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$82.756
Per500 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Gammagard S/D units and claim line

Enter the dose given to get the J1566 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Gammagard S/D NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Gammagard S/D NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00944-2656-03J1566Takeda Pharmaceuticals America, Inc.110
00944-2658-04J1566Takeda Pharmaceuticals America, Inc.120

Gammagard S/D: common questions

What is the J-code for Gammagard S/D?
Gammagard S/D is billed under HCPCS J1566 — Injection, immune globulin, intravenous, lyophilized (e.g., powder), not otherwise specified, 500 mg. One billing unit is 500 mg. CMS's crosswalk lists 2 Gammagard S/D NDCs under this code.
How many J1566 billing units are in a package of Gammagard S/D?
CMS lists 10 to 20 billing units per package, depending on the NDC, where one unit is 500 mg. Units to report are based on the dose given, not the package.
Is J1566 a CPT code?
No. J1566 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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