In short

Herceptin Hylecta is billed under HCPCS J9356 — Injection, trastuzumab, 10 mg and hyaluronidase-oysk. One billing unit is 10 mg. CMS's crosswalk lists 1 Herceptin Hylecta NDC under this code.

J9356 code details

Reference

J9356
Injection, trastuzumab, 10 mg and hyaluronidase-oyskBilling unit: 10 mg
Labelers
Genentech, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$58.038
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Herceptin Hylecta units and claim line

Enter the dose given to get the J9356 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Herceptin Hylecta NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Herceptin Hylecta NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
50242-0077-01J9356Genentech, Inc.660

Herceptin Hylecta: common questions

What is the J-code for Herceptin Hylecta?
Herceptin Hylecta is billed under HCPCS J9356 — Injection, trastuzumab, 10 mg and hyaluronidase-oysk. One billing unit is 10 mg. CMS's crosswalk lists 1 Herceptin Hylecta NDC under this code.
How many J9356 billing units are in a package of Herceptin Hylecta?
CMS lists 60 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
Is J9356 a CPT code?
No. J9356 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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