In short

Hercessi is billed under HCPCS Q5146 — Injection, trastuzumab-strf (hercessi), biosimilar, 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 2 Hercessi NDCs under this code.

Q5146 code details

Reference

Q5146
Injection, trastuzumab-strf (hercessi), biosimilar, 10 mgBilling unit: 10 mg
Labelers
Accord BioPharma, Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$30.255
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: 8% of reference add-on applied. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Hercessi units and claim line

Enter the dose given to get the Q5146 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Hercessi NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Hercessi NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
69448-0015-05Q5146Accord BioPharma, Inc115
69448-0016-11Q5146Accord BioPharma, Inc142

Hercessi: common questions

What is the HCPCS code for Hercessi?
Hercessi is billed under HCPCS Q5146 — Injection, trastuzumab-strf (hercessi), biosimilar, 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 2 Hercessi NDCs under this code.
How many Q5146 billing units are in a package of Hercessi?
CMS lists 15 to 42 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
Is Q5146 a CPT code?
No. Q5146 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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