In short

Hycamtin is billed under HCPCS J8705 — Topotecan, oral, 0.25 mg. One billing unit is 0.25 mg. CMS's crosswalk lists 2 Hycamtin NDCs under this code.

J8705 code details

Reference

J8705
Topotecan, oral, 0.25 mgBilling unit: 0.25 mg
Labelers
Sandoz Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$125.461
Per0.25 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Hycamtin units and claim line

Enter the dose given to get the J8705 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Hycamtin NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Hycamtin NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
66758-0101-11J8705Sandoz Inc.1010
66758-0102-11J8705Sandoz Inc.1040

Hycamtin: common questions

What is the J-code for Hycamtin?
Hycamtin is billed under HCPCS J8705 — Topotecan, oral, 0.25 mg. One billing unit is 0.25 mg. CMS's crosswalk lists 2 Hycamtin NDCs under this code.
How many J8705 billing units are in a package of Hycamtin?
CMS lists 10 to 40 billing units per package, depending on the NDC, where one unit is 0.25 mg. Units to report are based on the dose given, not the package.
Is J8705 a CPT code?
No. J8705 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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