In short

Hydroxocobalamin IM is billed under HCPCS J3425 — Injection, hydroxocobalamin, intramuscular, 10 mcg. One billing unit is 10 mcg. CMS's crosswalk lists 1 Hydroxocobalamin IM NDC under this code.

J3425 code details

Reference

J3425
Injection, hydroxocobalamin, intramuscular, 10 mcgBilling unit: 10 mcg
Labelers
Actavis Pharma, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.007
Per10 mcg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Hydroxocobalamin IM units and claim line

Enter the dose given to get the J3425 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Hydroxocobalamin IM NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Hydroxocobalamin IM NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00591-2888-30J3425Actavis Pharma, Inc.303000

Hydroxocobalamin IM: common questions

What is the J-code for Hydroxocobalamin IM?
Hydroxocobalamin IM is billed under HCPCS J3425 — Injection, hydroxocobalamin, intramuscular, 10 mcg. One billing unit is 10 mcg. CMS's crosswalk lists 1 Hydroxocobalamin IM NDC under this code.
How many J3425 billing units are in a package of Hydroxocobalamin IM?
CMS lists 3,000 billing units per package, depending on the NDC, where one unit is 10 mcg. Units to report are based on the dose given, not the package.
Is J3425 a CPT code?
No. J3425 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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