In short

Hydroxyzine HCl is billed under HCPCS J3410 — Injection, hydroxyzine hcl, up to 25 mg. One billing unit is 25 mg. CMS's crosswalk lists 6 Hydroxyzine HCl NDCs under this code.

J3410 code details

Reference

J3410
Injection, hydroxyzine hcl, up to 25 mgBilling unit: 25 mg
Labelers
American Regent, Inc.; HF Acquisition Co. LLC, DBA HealthFirst; Henry Schein Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$14.113
Per25 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Hydroxyzine HCl units and claim line

Enter the dose given to get the J3410 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Hydroxyzine HCl NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Hydroxyzine HCl NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00404-9877-01J3410Henry Schein Inc.12
00404-9878-02J3410Henry Schein Inc.24
00517-4201-25J3410American Regent, Inc.25 × 125
00517-5601-25J3410American Regent, Inc.25 × 150
00517-5602-25J3410American Regent, Inc.25 × 2100
51662-1649-03J3410HF Acquisition Co. LLC, DBA HealthFirst25 × 125

Hydroxyzine HCl: common questions

What is the J-code for Hydroxyzine HCl?
Hydroxyzine HCl is billed under HCPCS J3410 — Injection, hydroxyzine hcl, up to 25 mg. One billing unit is 25 mg. CMS's crosswalk lists 6 Hydroxyzine HCl NDCs under this code.
How many J3410 billing units are in a package of Hydroxyzine HCl?
CMS lists 2 to 100 billing units per package, depending on the NDC, where one unit is 25 mg. Units to report are based on the dose given, not the package.
Is J3410 a CPT code?
No. J3410 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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