In short

Khapzory is billed under HCPCS J0642 — Injection, levoleucovorin (khapzory), 0.5 mg. One billing unit is 0.5 mg. CMS's crosswalk lists 1 Khapzory NDC under this code.

J0642 code details

Reference

J0642
Injection, levoleucovorin (khapzory), 0.5 mgBilling unit: 0.5 mg
Labelers
Acrotech Biopharma LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$1.336
Per0.5 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Khapzory units and claim line

Enter the dose given to get the J0642 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Khapzory NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Khapzory NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
72893-0004-01J0642Acrotech Biopharma LLC1350

Khapzory: common questions

What is the J-code for Khapzory?
Khapzory is billed under HCPCS J0642 — Injection, levoleucovorin (khapzory), 0.5 mg. One billing unit is 0.5 mg. CMS's crosswalk lists 1 Khapzory NDC under this code.
How many J0642 billing units are in a package of Khapzory?
CMS lists 350 billing units per package, depending on the NDC, where one unit is 0.5 mg. Units to report are based on the dose given, not the package.
Is J0642 a CPT code?
No. J0642 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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