HCPCS drug code · CMS crosswalk
Leucovorin Calcium J-Code / HCPCS Code
In short
Leucovorin Calcium is billed under HCPCS J0643 — Injection, leucovorin calcium, not otherwise specified, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 35 Leucovorin Calcium NDCs under this code.
Reference
- J0643
- Injection, leucovorin calcium, not otherwise specified, 1 mgBilling unit: 1 mg
- Labelers
- BluePoint Laboratories; FreseniUS Kabi USA, LLC; Glenmark Pharmaceuticals Inc., Usa; Hikma Pharmaceuticals USA Inc.; Meitheal Pharmaceuticals Inc.; Mylan Institutional LLC; Sagent Pharmaceuticals; Slate Run Pharmaceuticals
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Added October 2026. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Leucovorin Calcium units and claim line
Enter the dose given to get the J0643 units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Leucovorin Calcium NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 00143-9368-01 | J0643 | Hikma Pharmaceuticals USA Inc. | 1 | 200 |
| 00143-9552-01 | J0643 | Hikma Pharmaceuticals USA Inc. | 1 | 350 |
| 00143-9553-01 | J0643 | Hikma Pharmaceuticals USA Inc. | 1 | 200 |
| 00143-9554-01 | J0643 | Hikma Pharmaceuticals USA Inc. | 1 | 100 |
| 00143-9555-01 | J0643 | Hikma Pharmaceuticals USA Inc. | 1 | 50 |
| 25021-0813-10 | J0643 | Sagent Pharmaceuticals | 10 × 1 | 500 |
| 25021-0814-30 | J0643 | Sagent Pharmaceuticals | 1 | 100 |
| 25021-0815-30 | J0643 | Sagent Pharmaceuticals | 1 | 200 |
| 25021-0816-30 | J0643 | Sagent Pharmaceuticals | 1 | 350 |
| 25021-0816-67 | J0643 | Sagent Pharmaceuticals | 1 | 350 |
| 25021-0828-50 | J0643 | Sagent Pharmaceuticals | 1 | 500 |
| 63323-0631-10 | J0643 | FreseniUS Kabi USA, LLC | 10 | 100 |
| 63323-0631-50 | J0643 | FreseniUS Kabi USA, LLC | 50 | 500 |
| 63323-0710-50 | J0643 | FreseniUS Kabi USA, LLC | 1 | 200 |
| 63323-0711-00 | J0643 | FreseniUS Kabi USA, LLC | 1 | 500 |
| 67457-0528-10 | J0643 | Mylan Institutional LLC | 1 | 100 |
| 67457-0529-20 | J0643 | Mylan Institutional LLC | 1 | 200 |
| 67457-0530-35 | J0643 | Mylan Institutional LLC | 1 | 350 |
| 68001-0416-36 | J0643 | BluePoint Laboratories | 1 | 100 |
| 68001-0417-37 | J0643 | BluePoint Laboratories | 1 | 200 |
| 68001-0418-38 | J0643 | BluePoint Laboratories | 1 | 350 |
| 68001-0648-36 | J0643 | BluePoint Laboratories | 1 | 100 |
| 68001-0649-37 | J0643 | BluePoint Laboratories | 1 | 200 |
| 68001-0650-38 | J0643 | BluePoint Laboratories | 1 | 350 |
| 68462-0767-35 | J0643 | Glenmark Pharmaceuticals Inc., Usa | 1 | 350 |
| 70436-0116-82 | J0643 | Slate Run Pharmaceuticals | 10 × 1 | 500 |
| 70436-0117-80 | J0643 | Slate Run Pharmaceuticals | 1 | 100 |
| 70436-0118-80 | J0643 | Slate Run Pharmaceuticals | 1 | 200 |
| 70436-0119-80 | J0643 | Slate Run Pharmaceuticals | 1 | 350 |
| 70436-0120-80 | J0643 | Slate Run Pharmaceuticals | 1 | 500 |
| 71288-0160-10 | J0643 | Meitheal Pharmaceuticals Inc. | 1 | 50 |
| 71288-0161-20 | J0643 | Meitheal Pharmaceuticals Inc. | 1 | 100 |
| 71288-0162-30 | J0643 | Meitheal Pharmaceuticals Inc. | 1 | 200 |
| 71288-0163-30 | J0643 | Meitheal Pharmaceuticals Inc. | 1 | 350 |
| 71288-0164-50 | J0643 | Meitheal Pharmaceuticals Inc. | 1 | 500 |
Leucovorin Calcium: common questions
- What is the J-code for Leucovorin Calcium?
- Leucovorin Calcium is billed under HCPCS J0643 — Injection, leucovorin calcium, not otherwise specified, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 35 Leucovorin Calcium NDCs under this code.
- How many J0643 billing units are in a package of Leucovorin Calcium?
- CMS lists 50 to 500 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
- Is J0643 a CPT code?
- No. J0643 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.