In short

Levofloxacin is billed under HCPCS J1956 — Injection, levofloxacin, 250 mg. One billing unit is 250 mg. CMS's crosswalk lists 15 Levofloxacin NDCs under this code.

J1956 code details

Reference

J1956
Injection, levofloxacin, 250 mgBilling unit: 250 mg
Labelers
Hikma Pharmaceuticals USA Inc.; Pfizer Inc; Sagent Pharmaceuticals; WG Critical Care, LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$2.565
Per250 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Levofloxacin units and claim line

Enter the dose given to get the J1956 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Levofloxacin NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Levofloxacin NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00143-9315-24J1956Hikma Pharmaceuticals USA Inc.24 × 5024
00143-9316-24J1956Hikma Pharmaceuticals USA Inc.24 × 10048
00143-9317-24J1956Hikma Pharmaceuticals USA Inc.24 × 15072
00143-9720-24J1956Hikma Pharmaceuticals USA Inc.24 × 15072
00143-9721-24J1956Hikma Pharmaceuticals USA Inc.24 × 10048
00143-9722-24J1956Hikma Pharmaceuticals USA Inc.24 × 5024
00409-2220-24J1956Pfizer Inc24 × 5024
00409-3330-24J1956Pfizer Inc24 × 10048
00409-4444-24J1956Pfizer Inc24 × 15072
25021-0132-81J1956Sagent Pharmaceuticals24 × 5024
25021-0132-82J1956Sagent Pharmaceuticals24 × 10048
25021-0132-83J1956Sagent Pharmaceuticals24 × 15072
44567-0435-24J1956WG Critical Care, LLC24 × 5024
44567-0436-24J1956WG Critical Care, LLC24 × 10048
44567-0437-24J1956WG Critical Care, LLC24 × 15072

Levofloxacin: common questions

What is the J-code for Levofloxacin?
Levofloxacin is billed under HCPCS J1956 — Injection, levofloxacin, 250 mg. One billing unit is 250 mg. CMS's crosswalk lists 15 Levofloxacin NDCs under this code.
How many J1956 billing units are in a package of Levofloxacin?
CMS lists 24 to 72 billing units per package, depending on the NDC, where one unit is 250 mg. Units to report are based on the dose given, not the package.
Is J1956 a CPT code?
No. J1956 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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