In short

CMS assigns Lupron Depot NDCs to 2 HCPCS codes: J1950 (per 3.75 mg), J9217 (per 7.5 mg). Which one applies depends on the product; the table lists each NDC with its code.

J1950 code detailsJ9217 code details

Reference

J1950
Injection, leuprolide acetate (for depot suspension), per 3.75 mgBilling unit: 3.75 mg
J9217
Leuprolide acetate (for depot suspension), 7.5 mgBilling unit: 7.5 mg
Labelers
AbbVie Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$1,799.052
Per3.75 mg
Coinsurance18.505%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Inflation-adjusted coinsurance. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$188.849
Per7.5 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Lupron Depot units and claim line

Enter the dose given to get the J1950 units and the NDC line for the CMS-1500 and the 837P. This builds the J1950 line; use the code page for J9217.

Enter the dose given to build the claim line.

Lupron Depot NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Lupron Depot NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00074-2108-03J1950AbbVie Inc.12
00074-2282-03J1950AbbVie Inc.13
00074-2440-03J1950AbbVie Inc.14
00074-3575-01J1950AbbVie Inc.112
00074-3641-03J1950AbbVie Inc.11
00074-3663-03J1950AbbVie Inc.13
00074-3779-03J1950AbbVie Inc.13
00074-9694-03J1950AbbVie Inc.18
00074-3346-03J9217AbbVie Inc.13
00074-3346-55J9217AbbVie Inc.13
00074-3473-03J9217AbbVie Inc.16
00074-3473-55J9217AbbVie Inc.16
00074-3642-03J9217AbbVie Inc.11
00074-3642-55J9217AbbVie Inc.11
00074-3683-03J9217AbbVie Inc.14
00074-3683-55J9217AbbVie Inc.14

Lupron Depot: common questions

What is the J-code for Lupron Depot?
CMS assigns Lupron Depot NDCs to 2 HCPCS codes: J1950 (per 3.75 mg), J9217 (per 7.5 mg). Which one applies depends on the product; the table lists each NDC with its code.
How many J1950 billing units are in a package of Lupron Depot?
CMS lists 1 to 12 billing units per package, depending on the NDC, where one unit is 3.75 mg. Units to report are based on the dose given, not the package.
How many J9217 billing units are in a package of Lupron Depot?
CMS lists 1 to 6 billing units per package, depending on the NDC, where one unit is 7.5 mg. Units to report are based on the dose given, not the package.
Is J1950 a CPT code?
No. J1950 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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