In short

Margenza is billed under HCPCS J9353 — Injection, margetuximab-cmkb, 5 mg. One billing unit is 5 mg. CMS's crosswalk lists 2 Margenza NDCs under this code.

J9353 code details

Reference

J9353
Injection, margetuximab-cmkb, 5 mgBilling unit: 5 mg
Labelers
MacroGenics, Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$56.046
Per5 mg
Coinsurance19.438%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Inflation-adjusted coinsurance. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Margenza units and claim line

Enter the dose given to get the J9353 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Margenza NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Margenza NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
74527-0022-02J9353MacroGenics, Inc1050
74527-0022-03J9353MacroGenics, Inc4 × 10200

Margenza: common questions

What is the J-code for Margenza?
Margenza is billed under HCPCS J9353 — Injection, margetuximab-cmkb, 5 mg. One billing unit is 5 mg. CMS's crosswalk lists 2 Margenza NDCs under this code.
How many J9353 billing units are in a package of Margenza?
CMS lists 50 to 200 billing units per package, depending on the NDC, where one unit is 5 mg. Units to report are based on the dose given, not the package.
Is J9353 a CPT code?
No. J9353 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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