In short

Nexviazyme is billed under HCPCS J0219 — Injection, avalglucosidase alfa-ngpt, 4 mg. One billing unit is 4 mg. CMS's crosswalk lists 1 Nexviazyme NDC under this code.

J0219 code details

Reference

J0219
Injection, avalglucosidase alfa-ngpt, 4 mgBilling unit: 4 mg
Labelers
Genzyme Corporation

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$83.816
Per4 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Nexviazyme units and claim line

Enter the dose given to get the J0219 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Nexviazyme NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Nexviazyme NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
58468-0426-01J0219Genzyme Corporation125

Nexviazyme: common questions

What is the J-code for Nexviazyme?
Nexviazyme is billed under HCPCS J0219 — Injection, avalglucosidase alfa-ngpt, 4 mg. One billing unit is 4 mg. CMS's crosswalk lists 1 Nexviazyme NDC under this code.
How many J0219 billing units are in a package of Nexviazyme?
CMS lists 25 billing units per package, depending on the NDC, where one unit is 4 mg. Units to report are based on the dose given, not the package.
Is J0219 a CPT code?
No. J0219 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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