How many J2305 billing units are in a package of Nitroglycerin?

CMS lists 10 to 250 billing units per package, depending on the NDC, where one unit is 5 mg. Units to report are based on the dose given, not the package.

No. J2305 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Nitroglycerin J-Code J2305 — Billing Units & NDCs

In short

Nitroglycerin is billed under HCPCS J2305 — Injection, nitroglycerin, 5 mg. One billing unit is 5 mg. CMS's crosswalk lists 3 Nitroglycerin NDCs under this code.

J2305 code details

Reference

J2305: Injection, nitroglycerin, 5 mgBilling unit: 5 mg
Labelers: American Regent, Inc.; HF Acquisition Co. LLC, DBA HealthFirst; Henry Schein Inc.

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$1.542

Per5 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Nitroglycerin units and claim line

Enter the dose given to get the J2305 units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 5 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Nitroglycerin NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Nitroglycerin NDCs in the CMS ASP crosswalk
NDC (11-digit)	HCPCS	Labeler	Package	Billing units per package
00404-9928-10	J2305	Henry Schein Inc.	10	10
00517-4810-25	J2305	American Regent, Inc.	25 × 10	250
51662-1386-01	J2305	HF Acquisition Co. LLC, DBA HealthFirst	10	10

Nitroglycerin: common questions

What is the J-code for Nitroglycerin?: Nitroglycerin is billed under HCPCS J2305 — Injection, nitroglycerin, 5 mg. One billing unit is 5 mg. CMS's crosswalk lists 3 Nitroglycerin NDCs under this code.
How many J2305 billing units are in a package of Nitroglycerin?: CMS lists 10 to 250 billing units per package, depending on the NDC, where one unit is 5 mg. Units to report are based on the dose given, not the package.
Is J2305 a CPT code?: No. J2305 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Nitroglycerin J-Code / HCPCS Code