How many Q5122 billing units are in a package of Nyvepria?

CMS lists 12 billing units per package, depending on the NDC, where one unit is 0.5 mg. Units to report are based on the dose given, not the package.

No. Q5122 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Nyvepria HCPCS Code Q5122 — Billing Units & NDCs

In short

Nyvepria is billed under HCPCS Q5122 — Injection, pegfilgrastim-apgf (nyvepria), biosimilar, 0.5 mg. One billing unit is 0.5 mg. CMS's crosswalk lists 1 Nyvepria NDC under this code.

Q5122 code details

Reference

Q5122: Injection, pegfilgrastim-apgf (nyvepria), biosimilar, 0.5 mgBilling unit: 0.5 mg
Labelers: Pfizer Inc

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$141.289

Per0.5 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: 8% of reference add-on applied. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Nyvepria units and claim line

Enter the dose given to get the Q5122 units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 0.5 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Nyvepria NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Nyvepria NDCs in the CMS ASP crosswalk
NDC (11-digit)	HCPCS	Labeler	Package	Billing units per package
00069-0324-01	Q5122	Pfizer Inc	0.6	12

Nyvepria: common questions

What is the HCPCS code for Nyvepria?: Nyvepria is billed under HCPCS Q5122 — Injection, pegfilgrastim-apgf (nyvepria), biosimilar, 0.5 mg. One billing unit is 0.5 mg. CMS's crosswalk lists 1 Nyvepria NDC under this code.
How many Q5122 billing units are in a package of Nyvepria?: CMS lists 12 billing units per package, depending on the NDC, where one unit is 0.5 mg. Units to report are based on the dose given, not the package.
Is Q5122 a CPT code?: No. Q5122 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Nyvepria HCPCS Code

Reference

Medicare Part B payment limit

Nyvepria units and claim line

Nyvepria NDCs and billing units

Nyvepria: common questions

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Reference

Medicare Part B payment limit

Nyvepria units and claim line

Nyvepria NDCs and billing units

Nyvepria: common questions

Other codes for the same drug

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