In short

CMS assigns Pemetrexed NDCs to 4 HCPCS codes: J9294 (per 10 mg), J9297 (per 10 mg), J9305 (per 10 mg), J9314 (per 10 mg). Which one applies depends on the product; the table lists each NDC with its code.

J9294 code detailsJ9297 code detailsJ9305 code detailsJ9314 code details

Reference

J9294
Injection, pemetrexed (hospira), not therapeutically equivalent to j9305, 10 mgBilling unit: 10 mg
J9297
Injection, pemetrexed (sandoz), not therapeutically equivalent to j9305, 10 mgBilling unit: 10 mg
J9305
Injection, pemetrexed, not otherwise specified, 10 mgBilling unit: 10 mg
J9314
Injection, pemetrexed (teva), not therapeutically equivalent to j9305, 10 mgBilling unit: 10 mg
Labelers
Apotex Corp; Athenex Pharmaceutical Division, LLC; BluePoint Laboratories; Dr. Reddy's Laboratories Inc.; Eugia US LLC; FreseniUS Kabi USA, LLC; Ingenus Pharmaceuticals LLC; Meitheal Pharmaceuticals Inc.and 7 more

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$3.678
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$4.879
Per10 mg
Coinsurance5.788%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Inflation-adjusted coinsurance. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$1.23
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$10.986
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Pemetrexed units and claim line

Enter the dose given to get the J9294 units and the NDC line for the CMS-1500 and the 837P. This builds the J9294 line; use the code page for J9297, J9305, J9314.

Enter the dose given to build the claim line.

Pemetrexed NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Pemetrexed NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00409-0004-04J9294Pfizer Inc40100
00409-0020-02J9294Pfizer Inc410
00409-0021-03J9294Pfizer Inc2050
00409-1045-01J9294Pfizer Inc410
00409-2188-01J9294Pfizer Inc2050
00409-3532-01J9294Pfizer Inc40100
00781-3518-76J9297Sandoz Inc.410
00781-3519-90J9297Sandoz Inc.2050
25021-0260-10J9305Sagent Pharmaceuticals110
25021-0261-50J9305Sagent Pharmaceuticals150
43598-0370-74J9305Dr. Reddy's Laboratories Inc.1100
43598-0386-62J9305Dr. Reddy's Laboratories Inc.110
43598-0387-11J9305Dr. Reddy's Laboratories Inc.150
50742-0341-01J9305Ingenus Pharmaceuticals LLC150
55150-0381-01J9305Eugia US LLC110
55150-0382-01J9305Eugia US LLC150
55150-0383-01J9305Eugia US LLC1100
60505-6065-00J9305Apotex Corp110
60505-6066-00J9305Apotex Corp150
60505-6067-00J9305Apotex Corp1100
60505-6068-00J9305Apotex Corp175
63323-0134-10J9305FreseniUS Kabi USA, LLC110
63323-0450-50J9305FreseniUS Kabi USA, LLC150
68001-0535-41J9305BluePoint Laboratories110
68001-0536-41J9305BluePoint Laboratories150
68001-0538-41J9305BluePoint Laboratories110
68001-0539-41J9305BluePoint Laboratories150
68001-0543-41J9305BluePoint Laboratories110
68001-0544-41J9305BluePoint Laboratories150
68001-0545-41J9305BluePoint Laboratories175
68001-0546-41J9305BluePoint Laboratories1100
70069-0834-01J9305Somerset Pharma, LLC110
70069-0835-01J9305Somerset Pharma, LLC150
70710-1654-01J9305Zydus Pharmaceuticals (USA) Inc.110
70710-1655-01J9305Zydus Pharmaceuticals (USA) Inc.150
70710-1674-01J9305Zydus Pharmaceuticals (USA) Inc.1100
70860-0202-10J9305Athenex Pharmaceutical Division, LLC110
70860-0203-50J9305Athenex Pharmaceutical Division, LLC150
71288-0147-50J9305Meitheal Pharmaceuticals Inc.175
71288-0148-51J9305Meitheal Pharmaceuticals Inc.1100
71288-0166-10J9305Meitheal Pharmaceuticals Inc.110
71288-0166-91J9305Meitheal Pharmaceuticals Inc.110
71288-0166-92J9305Meitheal Pharmaceuticals Inc.110
71288-0167-50J9305Meitheal Pharmaceuticals Inc.150
71288-0167-95J9305Meitheal Pharmaceuticals Inc.150
71288-0167-96J9305Meitheal Pharmaceuticals Inc.150
72603-0325-01J9305Northstar RxLLC110
72603-0425-01J9305Northstar RxLLC150
00480-4514-01J9314Teva Pharmaceuticals USA, Inc.2050
00480-4515-01J9314Teva Pharmaceuticals USA, Inc.40100
00480-4516-01J9314Teva Pharmaceuticals USA, Inc.410

Pemetrexed: common questions

What is the J-code for Pemetrexed?
CMS assigns Pemetrexed NDCs to 4 HCPCS codes: J9294 (per 10 mg), J9297 (per 10 mg), J9305 (per 10 mg), J9314 (per 10 mg). Which one applies depends on the product; the table lists each NDC with its code.
How many J9294 billing units are in a package of Pemetrexed?
CMS lists 10 to 100 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
How many J9297 billing units are in a package of Pemetrexed?
CMS lists 10 to 50 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
How many J9305 billing units are in a package of Pemetrexed?
CMS lists 10 to 100 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
How many J9314 billing units are in a package of Pemetrexed?
CMS lists 10 to 100 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
Is J9294 a CPT code?
No. J9294 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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