In short

Progesterone is billed under HCPCS J2675 — Injection, progesterone, per 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 5 Progesterone NDCs under this code.

J2675 code details

Reference

J2675
Injection, progesterone, per 50 mgBilling unit: 50 mg
Labelers
Actavis Pharma, Inc.; Eugia US LLC; FreseniUS Kabi USA, LLC; Hikma Pharmaceuticals USA Inc.; Xiromed, LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.623
Per50 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Progesterone units and claim line

Enter the dose given to get the J2675 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Progesterone NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Progesterone NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00143-9725-01J2675Hikma Pharmaceuticals USA Inc.1010
00591-3128-79J2675Actavis Pharma, Inc.1010
55150-0306-10J2675Eugia US LLC1010
63323-0261-10J2675FreseniUS Kabi USA, LLC1010
70700-0286-22J2675Xiromed, LLC1010

Progesterone: common questions

What is the J-code for Progesterone?
Progesterone is billed under HCPCS J2675 — Injection, progesterone, per 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 5 Progesterone NDCs under this code.
How many J2675 billing units are in a package of Progesterone?
CMS lists 10 billing units per package, depending on the NDC, where one unit is 50 mg. Units to report are based on the dose given, not the package.
Is J2675 a CPT code?
No. J2675 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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