In short

Prograf Granules is billed under HCPCS J7521 — Tacrolimus, granules, oral suspension, 0.1 mg. One billing unit is 0.1 mg. CMS's crosswalk lists 2 Prograf Granules NDCs under this code.

J7521 code details

Reference

J7521
Tacrolimus, granules, oral suspension, 0.1 mgBilling unit: 0.1 mg
Labelers
Astellas Pharma US, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$1.328
Per0.1 mg
Coinsurance0.997%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Inflation-adjusted coinsurance. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Prograf Granules units and claim line

Enter the dose given to get the J7521 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Prograf Granules NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Prograf Granules NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00469-1230-50J7521Astellas Pharma US, Inc.50100
00469-1330-50J7521Astellas Pharma US, Inc.50500

Prograf Granules: common questions

What is the J-code for Prograf Granules?
Prograf Granules is billed under HCPCS J7521 — Tacrolimus, granules, oral suspension, 0.1 mg. One billing unit is 0.1 mg. CMS's crosswalk lists 2 Prograf Granules NDCs under this code.
How many J7521 billing units are in a package of Prograf Granules?
CMS lists 100 to 500 billing units per package, depending on the NDC, where one unit is 0.1 mg. Units to report are based on the dose given, not the package.
Is J7521 a CPT code?
No. J7521 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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