In short

CMS assigns Prograf NDCs to 2 HCPCS codes: J7507 (per 1 mg), J7525 (per 5 mg). Which one applies depends on the product; the table lists each NDC with its code.

J7507 code detailsJ7525 code details

Reference

J7507
Tacrolimus, immediate release, oral, 1 mgBilling unit: 1 mg
J7525
Tacrolimus, parenteral, 5 mgBilling unit: 5 mg
Labelers
Astellas Pharma US, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.162
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$242.073
Per5 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Prograf units and claim line

Enter the dose given to get the J7507 units and the NDC line for the CMS-1500 and the 837P. This builds the J7507 line; use the code page for J7525.

Enter the dose given to build the claim line.

Prograf NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Prograf NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00469-0607-73J7507Astellas Pharma US, Inc.10050
00469-0617-73J7507Astellas Pharma US, Inc.100100
00469-0657-73J7507Astellas Pharma US, Inc.5 × 100500
00469-3016-01J7525Astellas Pharma US, Inc.10 × 110

Prograf: common questions

What is the J-code for Prograf?
CMS assigns Prograf NDCs to 2 HCPCS codes: J7507 (per 1 mg), J7525 (per 5 mg). Which one applies depends on the product; the table lists each NDC with its code.
How many J7507 billing units are in a package of Prograf?
CMS lists 50 to 500 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
How many J7525 billing units are in a package of Prograf?
CMS lists 10 billing units per package, depending on the NDC, where one unit is 5 mg. Units to report are based on the dose given, not the package.
Is J7507 a CPT code?
No. J7507 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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