In short

Ruxience is billed under HCPCS Q5119 — Injection, rituximab-pvvr, biosimilar, (ruxience), 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 2 Ruxience NDCs under this code.

Q5119 code details

Reference

Q5119
Injection, rituximab-pvvr, biosimilar, (ruxience), 10 mgBilling unit: 10 mg
Labelers
Pfizer Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$5.792
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: AMP-based payment limit. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Ruxience units and claim line

Enter the dose given to get the Q5119 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Ruxience NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Ruxience NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00069-0238-01Q5119Pfizer Inc1010
00069-0249-01Q5119Pfizer Inc5050

Ruxience: common questions

What is the HCPCS code for Ruxience?
Ruxience is billed under HCPCS Q5119 — Injection, rituximab-pvvr, biosimilar, (ruxience), 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 2 Ruxience NDCs under this code.
How many Q5119 billing units are in a package of Ruxience?
CMS lists 10 to 50 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
Is Q5119 a CPT code?
No. Q5119 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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