In short

Soliris is billed under HCPCS J1299 — Injection, eculizumab, 2 mg. One billing unit is 2 mg. CMS's crosswalk lists 1 Soliris NDC under this code.

J1299 code details

Reference

J1299
Injection, eculizumab, 2 mgBilling unit: 2 mg
Labelers
Alexion Pharmaceuticals, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$43.763
Per2 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Soliris units and claim line

Enter the dose given to get the J1299 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Soliris NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Soliris NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
25682-0001-01J1299Alexion Pharmaceuticals, Inc.30150

Soliris: common questions

What is the J-code for Soliris?
Soliris is billed under HCPCS J1299 — Injection, eculizumab, 2 mg. One billing unit is 2 mg. CMS's crosswalk lists 1 Soliris NDC under this code.
How many J1299 billing units are in a package of Soliris?
CMS lists 150 billing units per package, depending on the NDC, where one unit is 2 mg. Units to report are based on the dose given, not the package.
Is J1299 a CPT code?
No. J1299 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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