In short

CMS assigns Tobramycin NDCs to 2 HCPCS codes: J3260 (per 80 mg), J7682 (per 300 mg). Which one applies depends on the product; the table lists each NDC with its code.

J3260 code detailsJ7682 code details

Reference

J3260
Injection, tobramycin sulfate, up to 80 mgBilling unit: 80 mg
J7682
Tobramycin, inhalation solution, fda-approved final product, non-compounded, unit dose form, administered through dme, per 300 milligramsBilling unit: 300 mg
Labelers
Lifestar Pharma; Prasco Laboratories; Teva Pharmaceuticals USA, Inc.; Xiromed, LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$2.345
Per80 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$11.404
Per300 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Tobramycin units and claim line

Enter the dose given to get the J3260 units and the NDC line for the CMS-1500 and the 837P. This builds the J3260 line; use the code page for J7682.

Enter the dose given to build the claim line.

Tobramycin NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Tobramycin NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
70700-0173-22J3260Xiromed, LLC115
00093-3750-28J7682Teva Pharmaceuticals USA, Inc.28 × 428
00093-3750-63J7682Teva Pharmaceuticals USA, Inc.56 × 456
66993-0195-94J7682Prasco Laboratories56 × 456
70756-0617-56J7682Lifestar Pharma56 × 456

Tobramycin: common questions

What is the J-code for Tobramycin?
CMS assigns Tobramycin NDCs to 2 HCPCS codes: J3260 (per 80 mg), J7682 (per 300 mg). Which one applies depends on the product; the table lists each NDC with its code.
How many J3260 billing units are in a package of Tobramycin?
CMS lists 15 billing units per package, depending on the NDC, where one unit is 80 mg. Units to report are based on the dose given, not the package.
How many J7682 billing units are in a package of Tobramycin?
CMS lists 28 to 56 billing units per package, depending on the NDC, where one unit is 300 mg. Units to report are based on the dose given, not the package.
Is J3260 a CPT code?
No. J3260 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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