In short

Tofidence is billed under HCPCS Q5133 — Injection, tocilizumab-bavi (tofidence), biosimilar, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 6 Tofidence NDCs under this code.

Q5133 code details

Reference

Q5133
Injection, tocilizumab-bavi (tofidence), biosimilar, 1 mgBilling unit: 1 mg
Labelers
Organon LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$4.706
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: 8% of reference add-on applied. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Tofidence units and claim line

Enter the dose given to get the Q5133 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Tofidence NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Tofidence NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
64406-0022-01Q5133Organon LLC10200
64406-0023-01Q5133Organon LLC20400
64406-0024-01Q5133Organon LLC480
78206-0200-01Q5133Organon LLC480
78206-0201-01Q5133Organon LLC20200
78206-0202-01Q5133Organon LLC20400

Tofidence: common questions

What is the HCPCS code for Tofidence?
Tofidence is billed under HCPCS Q5133 — Injection, tocilizumab-bavi (tofidence), biosimilar, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 6 Tofidence NDCs under this code.
How many Q5133 billing units are in a package of Tofidence?
CMS lists 80 to 400 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
Is Q5133 a CPT code?
No. Q5133 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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