HCPCS drug code · CMS crosswalk
Topotecan J-Code / HCPCS Code
In short
Topotecan is billed under HCPCS J9351 — Injection, topotecan, 0.1 mg. One billing unit is 0.1 mg. CMS's crosswalk lists 5 Topotecan NDCs under this code.
Reference
- J9351
- Injection, topotecan, 0.1 mgBilling unit: 0.1 mg
- Labelers
- Accord Healthcare Inc; Actavis Pharma, Inc.; FreseniUS Kabi USA, LLC; Pfizer Inc
Medicare Part B payment limit
CMS ASP filePayment limit per unit$2.067
Per0.1 mg
Coinsurance20%
Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Topotecan units and claim line
Enter the dose given to get the J9351 units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Topotecan NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 00409-0302-01 | J9351 | Pfizer Inc | 1 | 40 |
| 16729-0151-31 | J9351 | Accord Healthcare Inc | 1 | 40 |
| 16729-0243-31 | J9351 | Accord Healthcare Inc | 4 | 40 |
| 45963-0615-56 | J9351 | Actavis Pharma, Inc. | 1 | 40 |
| 63323-0762-10 | J9351 | FreseniUS Kabi USA, LLC | 1 | 40 |
Topotecan: common questions
- What is the J-code for Topotecan?
- Topotecan is billed under HCPCS J9351 — Injection, topotecan, 0.1 mg. One billing unit is 0.1 mg. CMS's crosswalk lists 5 Topotecan NDCs under this code.
- How many J9351 billing units are in a package of Topotecan?
- CMS lists 40 billing units per package, depending on the NDC, where one unit is 0.1 mg. Units to report are based on the dose given, not the package.
- Is J9351 a CPT code?
- No. J9351 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.