How many J0588 billing units are in a package of Xeomin?

CMS lists 50 to 200 billing units per package, depending on the NDC, where one unit is 1 unit. Units to report are based on the dose given, not the package.

No. J0588 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Xeomin J-Code J0588 — Billing Units & NDCs

In short

Xeomin is billed under HCPCS J0588 — Injection, incobotulinumtoxin a, 1 unit. One billing unit is 1 unit. CMS's crosswalk lists 5 Xeomin NDCs under this code.

J0588 code details

Reference

J0588: Injection, incobotulinumtoxin a, 1 unitBilling unit: 1 unit
Labelers: Merz North America, Inc.; Merz Pharmaceuticals, LLC

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$5.262

Per1 unit

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Xeomin units and claim line

Enter the dose given to get the J0588 units and the NDC line for the CMS-1500 and the 837P.

Dose given (unit)

HCPCS units (1 unit = 1 unit)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Xeomin NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Xeomin NDCs in the CMS ASP crosswalk
NDC (11-digit)	HCPCS	Labeler	Package	Billing units per package
00259-1605-01	J0588	Merz Pharmaceuticals, LLC	1	50
00259-1610-01	J0588	Merz Pharmaceuticals, LLC	1	100
00259-1620-01	J0588	Merz Pharmaceuticals, LLC	1	200
46783-0160-01	J0588	Merz North America, Inc.	1	100
46783-0161-01	J0588	Merz North America, Inc.	1	50

Xeomin: common questions

What is the J-code for Xeomin?: Xeomin is billed under HCPCS J0588 — Injection, incobotulinumtoxin a, 1 unit. One billing unit is 1 unit. CMS's crosswalk lists 5 Xeomin NDCs under this code.
How many J0588 billing units are in a package of Xeomin?: CMS lists 50 to 200 billing units per package, depending on the NDC, where one unit is 1 unit. Units to report are based on the dose given, not the package.
Is J0588 a CPT code?: No. J0588 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Xeomin J-Code / HCPCS Code