How many J0775 billing units are in a package of Xiaflex?

CMS lists 90 billing units per package, depending on the NDC, where one unit is 0.01 mg. Units to report are based on the dose given, not the package.

No. J0775 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Xiaflex J-Code J0775 — Billing Units & NDCs

In short

Xiaflex is billed under HCPCS J0775 — Injection, collagenase, clostridium histolyticum, 0.01 mg. One billing unit is 0.01 mg. CMS's crosswalk lists 1 Xiaflex NDC under this code.

J0775 code details

Reference

J0775: Injection, collagenase, clostridium histolyticum, 0.01 mgBilling unit: 0.01 mg
Labelers: Endo USA, Inc.

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$81.072

Per0.01 mg

Coinsurance17.086%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Inflation-adjusted coinsurance. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Xiaflex units and claim line

Enter the dose given to get the J0775 units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 0.01 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Xiaflex NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Xiaflex NDCs in the CMS ASP crosswalk
NDC (11-digit)	HCPCS	Labeler	Package	Billing units per package
66887-0003-01	J0775	Endo USA, Inc.	1	90

Xiaflex: common questions

What is the J-code for Xiaflex?: Xiaflex is billed under HCPCS J0775 — Injection, collagenase, clostridium histolyticum, 0.01 mg. One billing unit is 0.01 mg. CMS's crosswalk lists 1 Xiaflex NDC under this code.
How many J0775 billing units are in a package of Xiaflex?: CMS lists 90 billing units per package, depending on the NDC, where one unit is 0.01 mg. Units to report are based on the dose given, not the package.
Is J0775 a CPT code?: No. J0775 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Xiaflex J-Code / HCPCS Code