HCPCS drug code · CMS crosswalk
Yervoy J-Code / HCPCS Code
In short
Yervoy is billed under HCPCS J9228 — Injection, ipilimumab, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 2 Yervoy NDCs under this code.
Reference
- J9228
- Injection, ipilimumab, 1 mgBilling unit: 1 mg
- Labelers
- E.R. Squibb & Sons, L.L.C.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Yervoy units and claim line
Enter the dose given to get the J9228 units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Yervoy NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 00003-2327-11 | J9228 | E.R. Squibb & Sons, L.L.C. | 10 | 50 |
| 00003-2328-22 | J9228 | E.R. Squibb & Sons, L.L.C. | 40 | 200 |
Yervoy: common questions
- What is the J-code for Yervoy?
- Yervoy is billed under HCPCS J9228 — Injection, ipilimumab, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 2 Yervoy NDCs under this code.
- How many J9228 billing units are in a package of Yervoy?
- CMS lists 50 to 200 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
- Is J9228 a CPT code?
- No. J9228 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.