In short

Yesintek is billed under HCPCS Q5100 — Injection, ustekinumab-kfce (yesintek), biosimilar, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 4 Yesintek NDCs under this code.

Q5100 code details

Reference

Q5100
Injection, ustekinumab-kfce (yesintek), biosimilar, 1 mgBilling unit: 1 mg
Labelers
Biocon Biologics Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$3.08
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: "lesser of" methodology applied; 8% of reference add-on applied. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Yesintek units and claim line

Enter the dose given to get the Q5100 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Yesintek NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Yesintek NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
83257-0023-41Q5100Biocon Biologics Inc0.545
83257-0024-11Q5100Biocon Biologics Inc0.545
83257-0025-41Q5100Biocon Biologics Inc190
83257-0026-11Q5100Biocon Biologics Inc26130

Yesintek: common questions

What is the HCPCS code for Yesintek?
Yesintek is billed under HCPCS Q5100 — Injection, ustekinumab-kfce (yesintek), biosimilar, 1 mg. One billing unit is 1 mg. CMS's crosswalk lists 4 Yesintek NDCs under this code.
How many Q5100 billing units are in a package of Yesintek?
CMS lists 45 to 130 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
Is Q5100 a CPT code?
No. Q5100 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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