In short

Zemdri is billed under HCPCS J0291 — Injection, plazomicin, 5 mg. One billing unit is 5 mg. CMS's crosswalk lists 1 Zemdri NDC under this code.

J0291 code details

Reference

J0291
Injection, plazomicin, 5 mgBilling unit: 5 mg
Labelers
Cipla USA, Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$3.519
Per5 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Zemdri units and claim line

Enter the dose given to get the J0291 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Zemdri NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Zemdri NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
69097-0820-96J0291Cipla USA, Inc.10 × 101000

Zemdri: common questions

What is the J-code for Zemdri?
Zemdri is billed under HCPCS J0291 — Injection, plazomicin, 5 mg. One billing unit is 5 mg. CMS's crosswalk lists 1 Zemdri NDC under this code.
How many J0291 billing units are in a package of Zemdri?
CMS lists 1,000 billing units per package, depending on the NDC, where one unit is 5 mg. Units to report are based on the dose given, not the package.
Is J0291 a CPT code?
No. J0291 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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