HCPCS Level II drug code
J0133 — Injection, acyclovir, 5 mg
In short
J0133 is the HCPCS Level II code for injection, acyclovir, 5 mg. CMS assigns NDCs for Acyclovir Sodium to it. One billing unit is 5 mg. The Medicare Part B payment limit is $0.048 per unit (October 1, 2026 through December 31, 2026).
Code
CMS HCPCS file- Descriptor
- Injection, acyclovir, 5 mg
- Short descriptor
- Acyclovir injection
- Code set
- HCPCS Level II, maintained by CMS
- Effective
- Jan 1, 2006
The billing unit is read from the descriptor. Confirm it against the CMS file before billing.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Units and claim line
Units = dose given ÷ 5 mg. For example, 500 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
NDCs billed under J0133
CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 9 NDCs to J0133 for Acyclovir Sodium. Billing units per package are CMS’s figures for this code’s unit.
| Drug | NDC (11-digit) | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| Acyclovir Sodium | 55150-0154-10 | Eugia US LLC | 10 × 10 | 1,000 |
| Acyclovir Sodium | 55150-0155-20 | Eugia US LLC | 10 × 20 | 2,000 |
| Acyclovir Sodium | 63323-0325-10 | FreseniUS Kabi USA, LLC | 10 × 20 | 1,000 |
| Acyclovir Sodium | 63323-0325-14 | FreseniUS Kabi USA, LLC | 10 × 10 | 1,000 |
| Acyclovir Sodium | 63323-0325-20 | FreseniUS Kabi USA, LLC | 10 × 20 | 2,000 |
| Acyclovir Sodium | 63323-0325-24 | FreseniUS Kabi USA, LLC | 10 × 20 | 2,000 |
| Acyclovir Sodium | 65219-0622-10 | FreseniUS Kabi USA, LLC | 10 × 10 | 1,000 |
| Acyclovir Sodium | 65219-0624-20 | FreseniUS Kabi USA, LLC | 10 × 20 | 2,000 |
| Acyclovir Sodium | 70436-0030-82 | Slate Run Pharmaceuticals | 10 × 10 | 1,000 |
J0133: common questions
- Is J0133 a CPT code?
- No. J0133 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
- What NDCs are billed under J0133?
- CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 9 NDCs under J0133, for Acyclovir Sodium. The table on this page shows each one with its billing units per package.
- What is the Medicare payment limit for J0133?
- $0.048 per 5 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
- What is one billing unit of J0133?
- One unit of J0133 is 5 mg, as stated in the code's descriptor. Units to report = dose given ÷ 5 mg. J-code billing units.