In short

J0290 is the HCPCS Level II code for injection, ampicillin sodium, 500 mg. CMS assigns NDCs for Ampicillin Sodium to it. One billing unit is 500 mg. The Medicare Part B payment limit is $0.619 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ0290
Billing unit500 mg
Descriptor
Injection, ampicillin sodium, 500 mg
Short descriptor
Ampicillin 500 mg inj
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 2000

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.619
Per500 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 500 mg. For example, 50000 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

NDCs billed under J0290

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 64 NDCs to J0290 for Ampicillin Sodium. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J0290 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Ampicillin Sodium00404-9803-99Henry Schein Inc.12
Ampicillin Sodium00404-9816-99Henry Schein Inc.12
Ampicillin Sodium00404-9818-99Henry Schein Inc.14
Ampicillin Sodium00781-3402-95Sandoz Inc.10 × 15
Ampicillin Sodium00781-3404-95Sandoz Inc.10 × 120
Ampicillin Sodium00781-3407-95Sandoz Inc.10 × 110
Ampicillin Sodium00781-3408-95Sandoz Inc.10 × 140
Ampicillin Sodium00781-3409-95Sandoz Inc.10 × 1200
Ampicillin Sodium00781-3412-92Sandoz Inc.10 × 120
Ampicillin Sodium00781-3413-92Sandoz Inc.10 × 140
Ampicillin Sodium00781-9242-95Sandoz Inc.10 × 15
Ampicillin Sodium00781-9261-95Sandoz Inc.10 × 120
Ampicillin Sodium00781-9273-95Sandoz Inc.10 × 140
Ampicillin Sodium00781-9402-95Sandoz Inc.10 × 15
Ampicillin Sodium00781-9404-95Sandoz Inc.10 × 120
Ampicillin Sodium00781-9407-95Sandoz Inc.10 × 110
Ampicillin Sodium00781-9408-95Sandoz Inc.10 × 140
Ampicillin Sodium00781-9409-95Sandoz Inc.10 × 1200
Ampicillin Sodium00781-9412-92Sandoz Inc.10 × 120
Ampicillin Sodium00781-9413-92Sandoz Inc.10 × 140
Ampicillin Sodium23155-0915-41Heritage Pharmaceuticals Inc.10 × 110
Ampicillin Sodium23155-0916-41Heritage Pharmaceuticals Inc.10 × 120
Ampicillin Sodium23155-0917-41Heritage Pharmaceuticals Inc.10 × 140
Ampicillin Sodium25021-0134-10Sagent Pharmaceuticals10 × 15
Ampicillin Sodium25021-0135-10Sagent Pharmaceuticals10 × 110
Ampicillin Sodium25021-0136-10Sagent Pharmaceuticals10 × 120
Ampicillin Sodium25021-0137-20Sagent Pharmaceuticals10 × 140
Ampicillin Sodium25021-0197-99Sagent Pharmaceuticals120
Ampicillin Sodium44567-0100-10WG Critical Care, LLC10 × 15
Ampicillin Sodium44567-0101-10WG Critical Care, LLC10 × 110
Ampicillin Sodium44567-0102-10WG Critical Care, LLC10 × 120
Ampicillin Sodium44567-0103-10WG Critical Care, LLC10 × 140
Ampicillin Sodium44567-0104-01WG Critical Care, LLC120
Ampicillin Sodium50090-4552-00A-S Medication Solutions14
Ampicillin Sodium51662-1560-03HF Acquisition Co. LLC, DBA HealthFirst10 × 140
Ampicillin Sodium51662-1595-03HF Acquisition Co. LLC, DBA HealthFirst10 × 15
Ampicillin Sodium55150-0113-10Eugia US LLC10 × 120
Ampicillin Sodium55150-0114-20Eugia US LLC10 × 140
Ampicillin Sodium55150-0115-99Eugia US LLC10 × 1200
Ampicillin Sodium65219-0014-10FreseniUS Kabi USA, LLC10 × 15
Ampicillin Sodium65219-0016-10FreseniUS Kabi USA, LLC10 × 110
Ampicillin Sodium65219-0018-10FreseniUS Kabi USA, LLC10 × 120
Ampicillin Sodium65219-0020-23FreseniUS Kabi USA, LLC10 × 140
Ampicillin Sodium66794-0220-41Piramal Critical Care Inc10 × 15
Ampicillin Sodium66794-0222-41Piramal Critical Care Inc10 × 120
Ampicillin Sodium66794-0223-41Piramal Critical Care Inc10 × 140
Ampicillin Sodium66794-0224-15Piramal Critical Care Inc120
Ampicillin Sodium70860-0112-15Athenex Pharmaceutical Division, LLC10 × 15
Ampicillin Sodium70860-0113-15Athenex Pharmaceutical Division, LLC10 × 110
Ampicillin Sodium70860-0114-15Athenex Pharmaceutical Division, LLC10 × 120
Ampicillin Sodium70860-0115-26Athenex Pharmaceutical Division, LLC10 × 140
Ampicillin Sodium70860-0118-99Athenex Pharmaceutical Division, LLC120
Ampicillin Sodium72485-0421-10Armas Pharmaceuticals Inc.10 × 120
Ampicillin Sodium72485-0422-10Armas Pharmaceuticals Inc.10 × 140
Ampicillin Sodium72485-0423-10Armas Pharmaceuticals Inc.120
Ampicillin Sodium72572-0016-10Civica, Inc.10 × 120
Ampicillin Sodium72572-0017-10Civica, Inc.10 × 140
Ampicillin Sodium72572-0093-10Civica, Inc.10 × 120
Ampicillin Sodium72572-0094-10Civica, Inc.10 × 140
Ampicillin Sodium72603-0221-10Northstar RxLLC10 × 110

Showing 60 of 64. The full list is in the CMS crosswalk file.

J0290: common questions

Is J0290 a CPT code?
No. J0290 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J0290?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 64 NDCs under J0290, for Ampicillin Sodium. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J0290?
$0.619 per 500 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J0290?
One unit of J0290 is 500 mg, as stated in the code's descriptor. Units to report = dose given ÷ 500 mg. J-code billing units.

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